Osteoarthritis (OA) of the knee is a complex peripheral joint disorder. This degenerative disease involving several joint tissues is characterized by damages to the articular cartilage. Pain is the primary symptom of OA and is the driving factor for patients to seek medical help. OA-associated pain is described as dull, aching pain that persists over time, but short episodes of more intense pain, known as flares, are also experience by many individuals.
Chemotherapy-induced peripheral neuropathy (CIPN) is a common and challenging complication arising from treatment with many commonly used anticancer agents. In particular, oxaliplatin-induced peripheral neuropathy (OIPN) occurring during treatment requires dose reduction or cessation of treatment.
Learn more about our preclinical services and capabilities with a focus on Oxaliplatin-induced Peripheral Neuropathy!