Focus on painful clinical situations

Persistent Postoperative Pain

Over 300 million worldwide surgeries are performed each year. The majority of patients have complete recovery without  complications. However, postoperative pain (POP) caused by surgical procedures remains major problem with severe impact on quality of life. Persistent POP has been defined by the International Association for the Study of Pain (IASP) as a clinical discomfort [...]

POSTOPERATIVE PAIN MANAGEMENT: A MULTIMODAL APPROACH

Postoperative pain (POP) is one of the most common types of acute pain. It can be defined as an anticipated and temporary increase in background pain present in surgical patients after a procedure. It is estimated that up to 80% of patients undergoing various surgical procedures experience pain and, of those, 40 to 60% experience [...]

Translational approaches of Irritable bowel syndrome: Visceral pain models

For this new blog, Laurent DIOP, Chief Scientific Officer at ANS Biotech, deals with the topic Irritable bowel syndrome (IBS). Prior to join ANS Biotech, Laurent contributed to drug and probiotic development projects in digestive well-being and visceral pain among various pharmaceutical and industrial companies. He led R&D programs designed to evaluate the efficacy of [...]

IRRITABLE BOWEL SYNDROME: CURRENT SITUATION

Irritable Bowel Syndrome (IBS) is a common chronic functional bowel disease with prevalence rates from 5 to 22%. IBS is defined by the coexistence of abdominal pain or discomfort and alteration in bowel habits without obvious organic abnormalities. Various treatments exist in this field, but what is the real current situation? The prescription drug market [...]

OSTEOARTHRITIS: CURRENT SITUATION

Musculoskeletal disorders represent the fourth cause of disability following neuropsychiatric disorders, cancers and cardiovascular diseases in both developed and developing countries. These injuries include a variety of disorders that cause pain in bones, joints, muscles, and surrounding structures. Osteoarthritis (OA) is considered as the most common of the articular disorders and is frequently cited as [...]

FOCUS ON OXALIPLATIN-INDUCED PERIPHERAL NEUROPATHY: MECHANISMS AND PHARMACOLOGY

For this first blog, Laurent DIOP, Chief Scientific Officer at ANS Biotech, would like to focus on Neuropathic Pain and more specifically on Chemotherapy-induced peripheral neuropathy (CIPN). Since its creation in 2006, ANS Biotech is fully involved in this thematic and daily serves its Clients, all around the world, using relevant in vivo models for [...]

NEUROPATHIC PAIN: WHERE ARE WE TODAY ?

Neuropathic pain refers to the pain caused by damage or disease affecting the somatosensory nervous system and symptomized by a hypersensitivity. Today, Neuropathic Pain is relatively common, afflicting 7% to 8% of the population around the world. Various treatments exist in this field, but what is the real current situation ? The Neuropathic Pain market [...]
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