Small molecules

Because of their specific action on receptors or neurotransmitters involved in pain processing, small molecules represent the majority of the drug discovery programs in the field of pain.


Therapeutic biologics have recently emerged as an attractive alternative to small molecules in the treatment of various painful diseases.
Biologics currently in development could dramatically change the clinical practice of pain management.


Probiotics are defined as live micro-organisms conferring a health benefit for the host when administered in adequate amounts. Growing evidence suggests that probiotics could affect emotional behavior, stress and pain-modulation systems.

Natural extracts

Medicinal properties of plants have been known for millennia.
Many painful diseases are treated using plant-derived medicines in the form of concoctions or concentrated plant extracts.


Toxins such as Botulinum toxin act by inhibiting muscle contraction and are useful for the treatment of medical disorders arising from excessive muscle contraction. Recently, their therapeutic uses have expanded exponentially to include a wide range of medical and surgical pain conditions.

ANS Biotech has an approval from the French National Agency for Safety and Health to use botulinum toxin.

Adeno-associated virus (AAV)

In the field of analgesic drug development, small-molecule therapeutics to probe novel targets in clinical trials are often unavailable. In this context, adeno-associated virus (AAV) gene therapy in rodent models of pain could fill an important gap in the drug development process.

ANS Biotech has an approval from the French Ministry of Education and Research to use genetically modified organisms of containment class 1.

Medical devices

When suffering from chronic pain, medication via available drug treatments is the first option. Other options including medical devices can also be a possibility. Medical devices act by modulating metabolic pathways or mimicking mechanisms of action of proven commercial drugs.

A broad range of dosing treatments

ANS Biotech offers a variety of customizable paradigms of treatment combined with the desired route of administration to meet your needs according to the PK of your test articles.

In all of our in vivo pain studies in rodents, we are prepared to use the classical administration routes such as: oral (PO), intravenous (IV), subcutaneous (SC), intraperitoneal (IP), intramuscular (IM). Our skilled lab technicians can also administer by the intrathecal (IT), intranasal (IN), intraarticular (IA), intraepidermal (IE) and intrarectal (IR) routes.

We constantly evaluate other types of test articles!