IN VIVO HIGH THROUGHPUT SCREENING IN MICE
If you are interested in a pain profile for your Discovery leads, but are restricted to the use of mice, then you should consider NOCIWayTM, a unique in vivo screening tool that has been reconfigured for use in this species.
Advantages include low compound requirements, more rapid turnaround (2 weeks) and increased cost-effectiveness.
NOCIWayTM simultaneously explores the activity of your compound in 5 fully validated pain models / tests across 3 different pain areas:
– Acute & tonic pain
– Inflammatory pain
– Visceral pain
– plus a behavioral toxicity assessment using the modified Irwin grid